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CBMS-05 COMPREHENSIVE METABOLOMIC ANALYSIS OF IDH1R132H CLINICAL GLIOMA SAMPLES REVEALS SUPPRESSION OF Β-OXIDATION DUE TO CARNITINE DEFICIENCY
BACKGROUND: Gliomas with isocitrate dehydrogenase 1 (IDH1) mutation have alterations in several enzyme activities, resulting in various metabolic changes. The aim of this study was to investigate the mechanism for the better prognosis of gliomas with IDH mutation by performing metabolomic analysis....
Autores principales: | Miyata, Satsuki, Tominaga, Kaoru, Sakashita, Eiji, Urabe, Masashi, Onuki, Yoshiyuki, Gomi, Akira, Yamaguchi, Takashi, Mieno, Makiko, Mizukami, Hiroaki, Kume, Akihiro, Ozawa, Keiya, Watanabe, Eijyu, Kawai, Kensuke, Endou, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213357/ http://dx.doi.org/10.1093/noajnl/vdz039.025 |
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