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ACT-01 THE SECOND GENERATION ANAPLASTIC LYMPHOMA KINASE (ALK) INHIBITOR CERITINIB EFFECTIVELY INDUCES CELL DEATH IN HUMAN GLIOBLASTOMA CELLS

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase which expresses only in the developmental stage of the brain during embryogenesis of human. On the other hand, a variety of ALK gene alterations, such as oncogenic fusion, activating point mutation, or wild type gene amplification, have...

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Detalles Bibliográficos
Autores principales: Kawauchi, Daisuke, Takahashi, Masamichi, Yamamuro, Shun, Kobayashi, Tatsuya, Uchida, Eita, Iwadate, Yasuo, Ichimura, Koichi, Tomiyama, Arata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213398/
http://dx.doi.org/10.1093/noajnl/vdz039.057