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TB-04 TERT PROMOTER MUTATION AS A SUSCEPTIBLE MOLECULAR MARKER OF BCNU LOCAL THERAPY

INTRODUCTION: Alkylating agents, including Temozolomide (TMZ) and CCNU (ACNU) have been widely accepted as a standard treatment in malignant gliomas. Several studies also demonstrated that BCNU wafer placement extended survival in glioblastoma patients. However, little study demonstrated gene-specif...

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Detalles Bibliográficos
Autores principales: Miyake, Shigeta, Tateishi, Kensuke, Sasame, Joe, Miyake, Yohei, Matsuyama, Shinichirou, Nakamura, Taishi, Yamamoto, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213408/
http://dx.doi.org/10.1093/noajnl/vdz039.047