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ACT-13 RESPONSE TO SEIZURE AND TUMOR-PROGRESSION BY TREATMENT WITH PERAMPANEL IN PATIENTS WITH GLIOMAS

BACKGROUND: Increased extracellular glutamate level activates AMPA type glutamate receptors (AMPA-receptor) and induces seizures. Antagonistic activation of AMPA-receptors inhibits epilepsy and glioma progression in vivo and in vitro studies. PATIENTS AND METHODS: (1) We tested perampanel (PER), an...

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Detalles Bibliográficos
Autores principales: Izumoto, Shuichi, Miyauchi, Masaru, Watanabe, Akira, Murakami, Saori, Tsuyuguchi, Naohiro, Kato, Amami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213410/
http://dx.doi.org/10.1093/noajnl/vdz039.062