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Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin
Bordetella pertussis, the causative agent of whopping cough, produces an adenylate cyclase toxin (CyaA) that plays a key role in the host colonization by targeting innate immune cells which express CD11b/CD18, the cellular receptor of CyaA. CyaA is also able to invade non-phagocytic cells, via a uni...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213728/ https://www.ncbi.nlm.nih.gov/pubmed/32392246 http://dx.doi.org/10.1371/journal.pone.0228606 |