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Inferring the immune response from repertoire sequencing

High-throughput sequencing of B- and T-cell receptors makes it possible to track immune repertoires across time, in different tissues, and in acute and chronic diseases or in healthy individuals. However, quantitative comparison between repertoires is confounded by variability in the read count of e...

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Detalles Bibliográficos
Autores principales: Puelma Touzel, Maximilian, Walczak, Aleksandra M., Mora, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213749/
https://www.ncbi.nlm.nih.gov/pubmed/32348312
http://dx.doi.org/10.1371/journal.pcbi.1007873