Developmental loss of MeCP2 from VIP interneurons impairs cortical function and behavior

Rett Syndrome is a devastating neurodevelopmental disorder resulting from mutations in the gene MECP2. Mutations of Mecp2 that are restricted to GABAergic cell types largely replicate the behavioral phenotypes associated with mouse models of Rett Syndrome, suggesting a pathophysiological role for in...

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Detalles Bibliográficos
Autores principales: Mossner, James M, Batista-Brito, Renata, Pant, Rima, Cardin, Jessica A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213975/
https://www.ncbi.nlm.nih.gov/pubmed/32343226
http://dx.doi.org/10.7554/eLife.55639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213975/
https://www.ncbi.nlm.nih.gov/pubmed/32343226
http://dx.doi.org/10.7554/eLife.55639

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