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Developmental loss of MeCP2 from VIP interneurons impairs cortical function and behavior
Rett Syndrome is a devastating neurodevelopmental disorder resulting from mutations in the gene MECP2. Mutations of Mecp2 that are restricted to GABAergic cell types largely replicate the behavioral phenotypes associated with mouse models of Rett Syndrome, suggesting a pathophysiological role for in...
Autores principales: | Mossner, James M, Batista-Brito, Renata, Pant, Rima, Cardin, Jessica A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213975/ https://www.ncbi.nlm.nih.gov/pubmed/32343226 http://dx.doi.org/10.7554/eLife.55639 |
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