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SPsimSeq: semi-parametric simulation of bulk and single-cell RNA-sequencing data

SUMMARY: SPsimSeq is a semi-parametric simulation method to generate bulk and single-cell RNA-sequencing data. It is designed to simulate gene expression data with maximal retention of the characteristics of real data. It is reasonably flexible to accommodate a wide range of experimental scenarios,...

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Detalles Bibliográficos
Autores principales: Assefa, Alemu Takele, Vandesompele, Jo, Thas, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214028/
https://www.ncbi.nlm.nih.gov/pubmed/32065619
http://dx.doi.org/10.1093/bioinformatics/btaa105