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Statistical significance of cluster membership for unsupervised evaluation of cell identities

MOTIVATION: Single-cell RNA-sequencing (scRNA-seq) allows us to dissect transcriptional heterogeneity arising from cellular types, spatio-temporal contexts and environmental stimuli. Transcriptional heterogeneity may reflect phenotypes and molecular signatures that are often unmeasured or unknown a...

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Detalles Bibliográficos
Autor principal: Chung, Neo Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214036/
https://www.ncbi.nlm.nih.gov/pubmed/32142108
http://dx.doi.org/10.1093/bioinformatics/btaa087