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Melatonin ameliorates renal fibroblast‐myofibroblast transdifferentiation and renal fibrosis through miR‐21‐5p regulation

Fibroblast‐myofibroblast transdifferentiation (FMT) is widely recognized as the major pathological feature of renal fibrosis. Although melatonin has exerted antifibrogenic activity in many diseases, its role in renal FMT remains unclear. In the present study, the aim was to explore the effect of mel...

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Detalles Bibliográficos
Autores principales: Li, Ningning, Wang, Zhan, Gao, Fenglan, Lei, Yanfei, Li, Zhenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214152/
https://www.ncbi.nlm.nih.gov/pubmed/32243691
http://dx.doi.org/10.1111/jcmm.15221