Cargando…
Melatonin ameliorates renal fibroblast‐myofibroblast transdifferentiation and renal fibrosis through miR‐21‐5p regulation
Fibroblast‐myofibroblast transdifferentiation (FMT) is widely recognized as the major pathological feature of renal fibrosis. Although melatonin has exerted antifibrogenic activity in many diseases, its role in renal FMT remains unclear. In the present study, the aim was to explore the effect of mel...
Autores principales: | Li, Ningning, Wang, Zhan, Gao, Fenglan, Lei, Yanfei, Li, Zhenzhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214152/ https://www.ncbi.nlm.nih.gov/pubmed/32243691 http://dx.doi.org/10.1111/jcmm.15221 |
Ejemplares similares
-
Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2016) -
miR‐200b ameliorates myofibroblast transdifferentiation in precancerous oral submucous fibrosis through targeting ZEB2
por: Liao, Yi‐Wen, et al.
Publicado: (2018) -
Melatonin Prevents Transforming Growth Factor-β1-Stimulated Transdifferentiation of Renal Interstitial Fibroblasts to Myofibroblasts by Suppressing Reactive Oxygen Species-Dependent Mechanisms
por: Kim, Jung-Yeon, et al.
Publicado: (2020) -
Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts
por: Razdan, Neetu, et al.
Publicado: (2018) -
miR‐21 promotes cardiac fibroblast‐to‐myofibroblast transformation and myocardial fibrosis by targeting Jagged1
por: Zhou, Xue‐liang, et al.
Publicado: (2018)