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Novel regulation of miR‐34a‐5p and HOTAIR by the combination of berberine and gefitinib  leading to inhibition of EMT in human lung cancer

HOTAIR is an important carcinogenic lncRNA and involves in tumorigenesis, and invasion. MiR‐34a‐5p functions as a tumour suppressor. However, the underlying mechanism of HOTAIR regulation especially in association with miR‐34a‐5p in non‐small‐cell lung cancer (NSCLC) has not been explored. Herein, w...

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Detalles Bibliográficos
Autores principales: Zheng, Fang, Li, Jing, Ma, ChangJu, Tang, XiaoJuan, Tang, Qing, Wu, JingJing, Chai, XiaoSu, Xie, Jianhui, Yang, Xiao‐bo, Hann, Swei Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214156/
https://www.ncbi.nlm.nih.gov/pubmed/32248643
http://dx.doi.org/10.1111/jcmm.15214