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Metformin suppresses proliferation and invasion of drug‐resistant breast cancer cells by activation of the Hippo pathway

Drug resistance limits the clinical efficacy of breast cancer therapies, and overexpression or activation of Yes‐associated protein (YAP) is common in drug‐resistant cancer cells. Thus, inhibition of YAP may reduce resistance to anti‐cancer drugs. Metformin (MET), a first‐line diabetes medication th...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Li, Juan, Chen, He, Wang, Ruiqi, Li, Pingping, Miao, Yi, Liu, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214175/
https://www.ncbi.nlm.nih.gov/pubmed/32281270
http://dx.doi.org/10.1111/jcmm.15241