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Metformin suppresses proliferation and invasion of drug‐resistant breast cancer cells by activation of the Hippo pathway
Drug resistance limits the clinical efficacy of breast cancer therapies, and overexpression or activation of Yes‐associated protein (YAP) is common in drug‐resistant cancer cells. Thus, inhibition of YAP may reduce resistance to anti‐cancer drugs. Metformin (MET), a first‐line diabetes medication th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214175/ https://www.ncbi.nlm.nih.gov/pubmed/32281270 http://dx.doi.org/10.1111/jcmm.15241 |