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Ligand‐specific recycling profiles determine distinct potential for chronic analgesic tolerance of delta‐opioid receptor (DOPr) agonists

δ‐opioid receptor (DOPr) agonists have analgesic efficacy in chronic pain models but development of tolerance limits their use for long‐term pain management. Although agonist potential for inducing acute analgesic tolerance has been associated with distinct patterns of DOPr internalization, the asso...

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Detalles Bibliográficos
Autores principales: Bagheri Tudashki, Hanieh, Haddad, Youssef, Charfi, Iness, Couture, Rejean, Pineyro, Graciela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214178/
https://www.ncbi.nlm.nih.gov/pubmed/32279433
http://dx.doi.org/10.1111/jcmm.15234