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PRMT5 silencing selectively affects MTAP‐deleted mesothelioma: In vitro evidence of a novel promising approach

Malignant mesothelioma (MM) is an aggressive asbestos‐related cancer of the serous membranes. Despite intensive treatment regimens, MM is still a fatal disease, mainly due to the intrinsic resistance to current therapies and the lack of predictive markers and new valuable molecular targets. Protein...

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Detalles Bibliográficos
Autores principales: Barbarino, Marcella, Cesari, Daniele, Bottaro, Maria, Luzzi, Luca, Namagerdi, Asadoor, Bertolino, Franca Maria, Bellan, Cristiana, Proietti, Fabrizio, Somma, Pasquale, Micheli, Mariacarolina, de Santi, Maria Margherita, Guazzo, Raffaella, Mutti, Luciano, Pirtoli, Luigi, Paladini, Piero, Indovina, Paola, Giordano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214180/
https://www.ncbi.nlm.nih.gov/pubmed/32301278
http://dx.doi.org/10.1111/jcmm.15213