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HOTAIR/miR‐125 axis‐mediated Hexokinase 2 expression promotes chemoresistance in human glioblastoma

Drug resistance is one of the major obstacles in glioblastoma (GBM) treatments using temozolomide (TMZ) based conventional chemotherapy. Recent studies revealed that Hexokinase 2 (HK2)‐mediated glycolysis is one of the sources, as the association of chemoresistance and the expression of HK2 was conf...

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Detalles Bibliográficos
Autores principales: Zhang, Jinnan, Chen, Guangyong, Gao, Yufei, Liang, Huaxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214183/
https://www.ncbi.nlm.nih.gov/pubmed/32279420
http://dx.doi.org/10.1111/jcmm.15233