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Efficient treatment of murine acute GvHD by in vitro expanded donor regulatory T cells

Acute graft-versus-host disease (aGvHD) is a frequent complication after allogeneic bone marrow/stem cell transplantation (BMT/SCT) induced by co-transplanted alloreactive conventional donor T cells. We previously demonstrated that the adoptive transfer of donor CD4(+)CD25(+)Foxp3(+) regulatory T ce...

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Detalles Bibliográficos
Autores principales: Riegel, Christin, Boeld, Tina J., Doser, Kristina, Huber, Elisabeth, Hoffmann, Petra, Edinger, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214258/
https://www.ncbi.nlm.nih.gov/pubmed/31719679
http://dx.doi.org/10.1038/s41375-019-0625-3