Blockade of thymic stromal lymphopoietin and CRTH2 attenuates airway inflammation in a murine model of allergic asthma

BACKGROUND/AIMS: Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that plays a key role in Th2-mediated inflammation, both directly by promoting the proliferation of naïve CD4 Th2 cells, and indirectly by activating dendritic cells (DCs). TSLP-activated DCs induce the expan...

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Detalles Bibliográficos
Autores principales: Lee, Hea Yon, Lee, Hwa Young, Hur, Jung, Kang, Hye Seon, Choi, Joon Young, Rhee, Chin Kook, Kang, Ji Young, Kim, Young Kyoon, Lee, Sook Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214371/
https://www.ncbi.nlm.nih.gov/pubmed/32183504
http://dx.doi.org/10.3904/kjim.2018.248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214371/
https://www.ncbi.nlm.nih.gov/pubmed/32183504
http://dx.doi.org/10.3904/kjim.2018.248

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