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Haplotype-specific PCR for NAT2 diplotyping

N-acetyltransferase 2 (NAT2) is an enzyme that acetylates many kinds of drugs, including the antituberculosis drug isoniazid. The NAT2 gene is highly diverse across populations. An individual can be classified as having a slow acetylator (SA), an intermediate acetylator (IA), or a rapid acetylator (...

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Detalles Bibliográficos
Autores principales: Wichukchinda, Nuanjun, Pakdee, Jirapa, Kunhapan, Punna, Imunchot, Wimala, Toyo-oka, Licht, Tokunaga, Katsushi, Mahasirimongkol, Surakameth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214404/
https://www.ncbi.nlm.nih.gov/pubmed/32411379
http://dx.doi.org/10.1038/s41439-020-0101-7