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Functional culture and in vitro genetic and small-molecule manipulation of adult mouse cardiomyocytes

Primary adult cardiomyocyte (aCM) represent the mature form of myocytes found in the adult heart. However, culture of aCMs in particular is challenged by poor survival and loss of phenotype, rendering extended in vitro experiments unfeasible. Here, we establish murine aCM culture methods that enhanc...

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Detalles Bibliográficos
Autores principales: Callaghan, Neal I., Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Lee, Xavier A., Ahsan Siraj, M., Driouchi, Amine, Yip, Christopher M., Husain, Mansoor, Simmons, Craig A., Gramolini, Anthony O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214405/
https://www.ncbi.nlm.nih.gov/pubmed/32393743
http://dx.doi.org/10.1038/s42003-020-0946-9