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Functional culture and in vitro genetic and small-molecule manipulation of adult mouse cardiomyocytes
Primary adult cardiomyocyte (aCM) represent the mature form of myocytes found in the adult heart. However, culture of aCMs in particular is challenged by poor survival and loss of phenotype, rendering extended in vitro experiments unfeasible. Here, we establish murine aCM culture methods that enhanc...
Autores principales: | Callaghan, Neal I., Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Lee, Xavier A., Ahsan Siraj, M., Driouchi, Amine, Yip, Christopher M., Husain, Mansoor, Simmons, Craig A., Gramolini, Anthony O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214405/ https://www.ncbi.nlm.nih.gov/pubmed/32393743 http://dx.doi.org/10.1038/s42003-020-0946-9 |
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