Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line

The determination of individual cell trajectories through a high-dimensional cell-state space is an outstanding challenge for understanding biological changes ranging from cellular differentiation to epigenetic responses of diseased cells upon drugging. We integrate experiments and theory to determi...

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Detalles Bibliográficos
Autores principales: Su, Yapeng, Ko, Melissa E., Cheng, Hanjun, Zhu, Ronghui, Xue, Min, Wang, Jessica, Lee, Jihoon W., Frankiw, Luke, Xu, Alexander, Wong, Stephanie, Robert, Lidia, Takata, Kaitlyn, Yuan, Dan, Lu, Yue, Huang, Sui, Ribas, Antoni, Levine, Raphael, Nolan, Garry P., Wei, Wei, Plevritis, Sylvia K., Li, Guideng, Baltimore, David, Heath, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214418/
https://www.ncbi.nlm.nih.gov/pubmed/32393797
http://dx.doi.org/10.1038/s41467-020-15956-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214418/
https://www.ncbi.nlm.nih.gov/pubmed/32393797
http://dx.doi.org/10.1038/s41467-020-15956-9

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