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Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
The determination of individual cell trajectories through a high-dimensional cell-state space is an outstanding challenge for understanding biological changes ranging from cellular differentiation to epigenetic responses of diseased cells upon drugging. We integrate experiments and theory to determi...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214418/ https://www.ncbi.nlm.nih.gov/pubmed/32393797 http://dx.doi.org/10.1038/s41467-020-15956-9 |