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Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity

Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens. Here we report that sepsis in mice caused by a defined four-member pathogen community isolate...

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Detalles Bibliográficos
Autores principales: Kim, Sangman M., DeFazio, Jennifer R., Hyoju, Sanjiv K., Sangani, Kishan, Keskey, Robert, Krezalek, Monika A., Khodarev, Nikolai N., Sangwan, Naseer, Christley, Scott, Harris, Katharine G., Malik, Ankit, Zaborin, Alexander, Bouziat, Romain, Ranoa, Diana R., Wiegerinck, Mara, Ernest, Jordan D., Shakhsheer, Baddr A., Fleming, Irma D., Weichselbaum, Ralph R., Antonopoulos, Dionysios A., Gilbert, Jack A., Barreiro, Luis B., Zaborina, Olga, Jabri, Bana, Alverdy, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214422/
https://www.ncbi.nlm.nih.gov/pubmed/32393794
http://dx.doi.org/10.1038/s41467-020-15545-w