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Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

Impaired cognitive functioning is a core feature of schizophrenia, and is hypothesized to be due to myelination as well as interneuron defects during adolescent prefrontal cortex (PFC) development. Here we report that in the apomorphine-susceptible (APO-SUS) rat model, which has schizophrenia-like f...

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Detalles Bibliográficos
Autores principales: Maas, Dorien A., Eijsink, Vivian D., Spoelder, Marcia, van Hulten, Josephus A., De Weerd, Peter, Homberg, Judith R., Vallès, Astrid, Nait-Oumesmar, Brahim, Martens, Gerard J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214427/
https://www.ncbi.nlm.nih.gov/pubmed/32393757
http://dx.doi.org/10.1038/s41467-020-16218-4