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Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia
Impaired cognitive functioning is a core feature of schizophrenia, and is hypothesized to be due to myelination as well as interneuron defects during adolescent prefrontal cortex (PFC) development. Here we report that in the apomorphine-susceptible (APO-SUS) rat model, which has schizophrenia-like f...
Autores principales: | Maas, Dorien A., Eijsink, Vivian D., Spoelder, Marcia, van Hulten, Josephus A., De Weerd, Peter, Homberg, Judith R., Vallès, Astrid, Nait-Oumesmar, Brahim, Martens, Gerard J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214427/ https://www.ncbi.nlm.nih.gov/pubmed/32393757 http://dx.doi.org/10.1038/s41467-020-16218-4 |
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