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FTSJ1 regulates tRNA 2ʹ-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide. The mechanisms underlying NSCLC tumorigenesis are incompletely understood. Transfer RNA (tRNA) modification is emerging as a novel regulatory mechanism for carcinogenesis. However, the role of tRNA modification in...

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Detalles Bibliográficos
Autores principales: He, Qihan, Yang, Lin, Gao, Kaiping, Ding, Peikun, Chen, Qianqian, Xiong, Juan, Yang, Wenhan, Song, Yi, Wang, Liang, Wang, Yejun, Ling, Lijuan, Wu, Weiming, Yan, Jisong, Zou, Peng, Chen, Yuhuan, Zhai, Rihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214438/
https://www.ncbi.nlm.nih.gov/pubmed/32393790
http://dx.doi.org/10.1038/s41419-020-2525-x