Multiplex precise base editing in cynomolgus monkeys

Common polygenic diseases result from compounded risk contributed by multiple genetic variants, meaning that simultaneous correction or introduction of single nucleotide variants is required for disease modeling and gene therapy. Here, we show precise, efficient, and simultaneous multiplex base edit...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhui, Aida, Tomomi, del Rosario, Ricardo C. H., Wilde, Jonathan J., Ding, Chenhui, Zhang, Xiaohui, Baloch, Zulqurain, Huang, Yan, Tang, Yu, Li, Duanduan, Lu, Hongyu, Zhou, Yang, Jiang, Minqing, Xu, Dongdong, Fang, Zhihao, Zheng, Zhanhong, Huang, Qunshan, Feng, Guoping, Yang, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214463/
https://www.ncbi.nlm.nih.gov/pubmed/32393762
http://dx.doi.org/10.1038/s41467-020-16173-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214463/
https://www.ncbi.nlm.nih.gov/pubmed/32393762
http://dx.doi.org/10.1038/s41467-020-16173-0

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