Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication

Cisplatin is a very effective chemotherapeutic, but severe and permanent hearing loss remains a prevalent side effect. The processes underpinning cisplatin-induced ototoxicity are not well understood. Gap junction channels composed of connexin (Cx) subunits allow for the passage of small molecules a...

Descripción completa

Detalles Bibliográficos
Autores principales: Abitbol, Julia, Beach, Rianne, Barr, Kevin, Esseltine, Jessica, Allman, Brian, Laird, Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214471/
https://www.ncbi.nlm.nih.gov/pubmed/32393745
http://dx.doi.org/10.1038/s41419-020-2551-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214471/
https://www.ncbi.nlm.nih.gov/pubmed/32393745
http://dx.doi.org/10.1038/s41419-020-2551-8

Ejemplares similares