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Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication
Cisplatin is a very effective chemotherapeutic, but severe and permanent hearing loss remains a prevalent side effect. The processes underpinning cisplatin-induced ototoxicity are not well understood. Gap junction channels composed of connexin (Cx) subunits allow for the passage of small molecules a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214471/ https://www.ncbi.nlm.nih.gov/pubmed/32393745 http://dx.doi.org/10.1038/s41419-020-2551-8 |