Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption

The ex vivo isolated perfused rat lung (IPL) model has been demonstrated to be a useful tool during drug development for studying pulmonary drug absorption. This study aims to investigate the potential use of IPL data to predict rat in vivo lung absorption. Absorption parameters determined from IPL...

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Detalles Bibliográficos
Autores principales: Eriksson, Johanna, Sjögren, Erik, Lennernäs, Hans, Thörn, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214485/
https://www.ncbi.nlm.nih.gov/pubmed/32394314
http://dx.doi.org/10.1208/s12248-020-00456-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214485/
https://www.ncbi.nlm.nih.gov/pubmed/32394314
http://dx.doi.org/10.1208/s12248-020-00456-x

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