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TIGIT Blockade: A Multipronged Approach to Target the HIV Reservoir
During chronic human immunodeficiency virus type 1 (HIV-1) infection, upregulation of inhibitory molecules contributes to effector cell dysfunction and exhaustion. This, in combination with the ability of HIV-1 to reside dormant in cellular reservoirs and escape immune recognition, makes the pathway...
Autores principales: | Holder, Kayla A., Grant, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214612/ https://www.ncbi.nlm.nih.gov/pubmed/32432050 http://dx.doi.org/10.3389/fcimb.2020.00175 |
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