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Stimulation of L‐type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells

Making high‐quality dopamine (DA)‐producing cells for basic biological or small molecule screening studies is critical for the development of novel therapeutics for disorders of the ventral midbrain. Currently, many ventral midbrain assays have low signal‐to‐noise ratio due to low levels of cellular...

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Detalles Bibliográficos
Autores principales: Jefri, Malvin, Bell, Scott, Peng, Huashan, Hettige, Nuwan, Maussion, Gilles, Soubannier, Vincent, Wu, Hanrong, Silveira, Heika, Theroux, Jean‐Francois, Moquin, Luc, Zhang, Xin, Aouabed, Zahia, Krishnan, Jeyashree, O'Leary, Liam A., Antonyan, Lilit, Zhang, Ying, McCarty, Vincent, Mechawar, Naguib, Gratton, Alain, Schuppert, Andreas, Durcan, Thomas M., Fon, Edward A., Ernst, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214648/
https://www.ncbi.nlm.nih.gov/pubmed/32154672
http://dx.doi.org/10.1002/sctm.18-0180