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Omiganan Enhances Imiquimod‐Induced Inflammatory Responses in Skin of Healthy Volunteers

Omiganan (OMN; a synthetic cationic peptide) and imiquimod (IMQ; a TLR7 agonist) have synergistic effects on interferon responses in vitro. The objective of this study was to translate this to a human model for proof‐of‐concept, and to explore the potential of OMN add‐on treatment for viral skin dis...

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Detalles Bibliográficos
Autores principales: Niemeyer‐van der Kolk, Tessa, Assil, Salma, Buters, Thomas P., Rijsbergen, Melanie, Klaassen, Erica S., Feiss, Gary, Florencia, Edwin, Prens, Errol P., Burggraaf, Jacobus, van Doorn, Martijn B.A., Rissmann, Robert, Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214655/
https://www.ncbi.nlm.nih.gov/pubmed/32043302
http://dx.doi.org/10.1111/cts.12741