A 3‐week nonalcoholic steatohepatitis mouse model shows elafibranor benefits on hepatic inflammation and cell death

The long duration of animal models represents a clear limitation to quickly evaluate the efficacy of drugs targeting nonalcoholic steatohepatitis (NASH). We, therefore, developed a rapid mouse model of liver inflammation (i.e., the mouse fed a high‐fat/high‐cholesterol diet, where cyclodextrin is co...

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Detalles Bibliográficos
Autores principales: Briand, François, Heymes, Christophe, Bonada, Lucile, Angles, Thibault, Charpentier, Julie, Branchereau, Maxime, Brousseau, Emmanuel, Quinsat, Marjolaine, Fazilleau, Nicolas, Burcelin, Rémy, Sulpice, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214663/
https://www.ncbi.nlm.nih.gov/pubmed/31981449
http://dx.doi.org/10.1111/cts.12735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214663/
https://www.ncbi.nlm.nih.gov/pubmed/31981449
http://dx.doi.org/10.1111/cts.12735

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