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Increased Plasma Levels of Mitochondrial DNA and Normal Inflammasome Gene Expression in Monocytes Characterize Patients With Septic Shock Due to Multidrug Resistant Bacteria

Introduction: The activity and regulation of inflammasome is receiving increasing attention in septic shock. Moreover, there is a growing body of evidence suggesting that mitochondrial DNA (mtDNA) can play a role as biomarker of disease severity and even mortality both in adults and children in crit...

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Detalles Bibliográficos
Autores principales: Busani, Stefano, De Biasi, Sara, Nasi, Milena, Paolini, Annamaria, Venturelli, Sophie, Tosi, Martina, Girardis, Massimo, Cossarizza, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214691/
https://www.ncbi.nlm.nih.gov/pubmed/32431703
http://dx.doi.org/10.3389/fimmu.2020.00768