Cargando…

Increased Plasma Levels of Mitochondrial DNA and Normal Inflammasome Gene Expression in Monocytes Characterize Patients With Septic Shock Due to Multidrug Resistant Bacteria

Introduction: The activity and regulation of inflammasome is receiving increasing attention in septic shock. Moreover, there is a growing body of evidence suggesting that mitochondrial DNA (mtDNA) can play a role as biomarker of disease severity and even mortality both in adults and children in crit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Busani, Stefano, De Biasi, Sara, Nasi, Milena, Paolini, Annamaria, Venturelli, Sophie, Tosi, Martina, Girardis, Massimo, Cossarizza, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214691/ https://www.ncbi.nlm.nih.gov/pubmed/32431703 http://dx.doi.org/10.3389/fimmu.2020.00768

Ejemplares similares

Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature
por: Mantovani, Elena, et al.
Publicado: (2018)

Early alterations of B cells in patients with septic shock: another piece in the complex puzzle of the immune response in sepsis
por: Girardis, Massimo, et al.
Publicado: (2013)

Adjunctive Immunotherapy With Polyclonal Ig-M Enriched Immunoglobulins for Septic Shock: From Bench to Bedside. The Rationale for a Personalized Treatment Protocol
por: Busani, Stefano, et al.
Publicado: (2021)

Early use of immunoglobulin in septic shock
por: Cavazzuti, IC, et al.
Publicado: (2010)

The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDR/XDR Infections
por: Busani, Stefano, et al.
Publicado: (2017)

Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia
por: Gibellini, Lara, et al.
Publicado: (2020)

Monocyte Distribution Width (MDW) as novel inflammatory marker with prognostic significance in COVID-19 patients
por: Riva, Giovanni, et al.
Publicado: (2021)

Plasma Cytokine Atlas Reveals the Importance of TH2 Polarization and Interferons in Predicting COVID-19 Severity and Survival
por: Gibellini, Lara, et al.
Publicado: (2022)

Prognostic immune markers identifying patients with severe COVID-19 who respond to tocilizumab
por: De Biasi, Sara, et al.
Publicado: (2023)

Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia
por: Lo Tartaro, Domenico, et al.
Publicado: (2022)

Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study
por: Girardis, Massimo, et al.
Publicado: (2009)

Patients Recovering from Severe COVID-19 Develop a Polyfunctional Antigen-Specific CD4+ T Cell Response
por: Paolini, Annamaria, et al.
Publicado: (2022)

Surfactant replacement might help recovery of low-compliance lung in severe COVID-19 pneumonia
por: Busani, Stefano, et al.
Publicado: (2020)

Natural Compounds Modulating Mitochondrial Functions
por: Gibellini, Lara, et al.
Publicado: (2015)

Detailed characterization of SARS-CoV-2-specific T and B cells after infection or heterologous vaccination
por: Lo Tartaro, Domenico, et al.
Publicado: (2023)

PSP/reg: a new stone in sepsis biomarkers?
por: Busani, Stefano, et al.
Publicado: (2012)

Balanced crystalloids for septic shock resuscitation
por: Corrêa, Thiago Domingos, et al.
Publicado: (2016)

Revisited Hyperoxia Pathophysiology in the Perioperative Setting: A Narrative Review
por: Busani, Stefano, et al.
Publicado: (2021)

Role of Selective Digestive Decontamination in the Prevention of Ventilator-Associated Pneumonia in COVID-19 Patients: A Pre-Post Observational Study
por: Biagioni, Emanuela, et al.
Publicado: (2023)

Effects of sepsis resuscitation bundle in cirrhotic patients with septic shock
por: Rinaldi, L, et al.
Publicado: (2010)

A challenging case of pregnancy with placenta accreta and very rare irregular antibodies versus Cromer blood group system: a case report
por: Busani, Stefano, et al.
Publicado: (2015)

Effects of cytokine blocking agents on hospital mortality in patients admitted to ICU with acute respiratory distress syndrome by SARS-CoV-2 infection: retrospective cohort study
por: Coloretti, Irene, et al.
Publicado: (2021)

Interfering with ROS Metabolism in Cancer Cells: The Potential Role of Quercetin
por: Gibellini, Lara, et al.
Publicado: (2010)

Anti-TNF-α Drugs Differently Affect the TNFα-sTNFR System and Monocyte Subsets in Patients with Psoriasis
por: Gibellini, Lara, et al.
Publicado: (2016)

Hospital staff education on severe sepsis/septic shock and hospital mortality: an original hypothesis
por: Capuzzo, Maurizia, et al.
Publicado: (2012)

Early apoptosis of blood monocytes in the septic host: is it a mechanism of protection in the event of septic shock?
por: Giamarellos-Bourboulis, Evangelos J, et al.
Publicado: (2006)

Outcomes of septic shock due to multidrug resistant bacteraemia treated with phosphomycine
por: Theohari, A, et al.
Publicado: (2015)

Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids
por: Borella, Rebecca, et al.
Publicado: (2019)

The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome
por: Donati, Abele, et al.
Publicado: (2013)

Effect of interleukin-31 on septic shock through regulating inflammasomes and interleukin-1β
por: Gu, Xuyun, et al.
Publicado: (2018)

The clinical impact of multidrug-resistant gram-negative bacilli in the management of septic shock
por: Pop-Vicas, Aurora, et al.
Publicado: (2014)

Differences in monocyte subsets are associated with short‐term survival in patients with septic shock
por: Hortová‐Kohoutková, Marcela, et al.
Publicado: (2020)

Impact of Pre-Analytical Time on the Recovery of Pathogens from Blood Cultures: Results from a Large Retrospective Survey
por: Venturelli, Claudia, et al.
Publicado: (2017)

Influence of vasopressor agent in pediatric septic shock mortality
por: Mangia, CMF, et al.
Publicado: (2011)

Impaired Mitochondrial Morphology and Functionality in Lonp1(wt/−) Mice
por: De Gaetano, Anna, et al.
Publicado: (2020)

Empiric treatment of patients with sepsis and septic shock and place in therapy of cefiderocol: a systematic review and expert opinion statement
por: Cortegiani, Andrea, et al.
Publicado: (2022)

Decreased monocyte surface expression of HLA-DQ is associated with prolonged duration of septic shock
por: Voglic, SJ, et al.
Publicado: (2002)

Caspase-8 inhibition represses initial human monocyte activation in septic shock model
por: Oliva-Martin, Maria Jose, et al.
Publicado: (2016)

CIITA promoter polymorphism impairs monocytes HLA-DR expression in patients with septic shock
por: Miatello, Jordi, et al.
Publicado: (2022)

Monocyte-to-HDL ratio and non-HDL cholesterol were predictors of septic shock in newborns
por: da Fonseca, Fernanda Andrade Macaferri, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8ntu8mf1i71i1uhl3c4dgakveg