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T-Bet Expression Mediated by the mTOR Pathway Influences CD4(+) T Cell Count in Mice With Lethal Candida Sepsis

The sustained high morbidity and mortality of Candida sepsis are mainly caused by compromise of host immunity. Clinically, it is often manifested as a significant decrease in CD4(+) T cell count, although the mechanism is unclear. We established a lethal mice Candida sepsis model and used Murine Sep...

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Detalles Bibliográficos
Autores principales: Bai, Guangxu, Wang, Hao, Han, Wen, Cui, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214724/
https://www.ncbi.nlm.nih.gov/pubmed/32431684
http://dx.doi.org/10.3389/fmicb.2020.00835