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Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters

The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. Alternative promoters drive expression of Rbfox1 tr...

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Detalles Bibliográficos
Autores principales: Casanovas, Sonia, Schlichtholz, Laura, Mühlbauer, Sophia, Dewi, Sri, Schüle, Martin, Strand, Dennis, Strand, Susanne, Zografidou, Lea, Winter, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214753/
https://www.ncbi.nlm.nih.gov/pubmed/32431595
http://dx.doi.org/10.3389/fnmol.2020.00066