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Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters
The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. Alternative promoters drive expression of Rbfox1 tr...
Autores principales: | Casanovas, Sonia, Schlichtholz, Laura, Mühlbauer, Sophia, Dewi, Sri, Schüle, Martin, Strand, Dennis, Strand, Susanne, Zografidou, Lea, Winter, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214753/ https://www.ncbi.nlm.nih.gov/pubmed/32431595 http://dx.doi.org/10.3389/fnmol.2020.00066 |
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