QSAR-driven rational design of novel DNA methyltransferase 1 inhibitors

DNA methylation, an epigenetic modification, is mediated by DNA methyltransferases (DNMTs), a family of enzymes. Inhibitions of these enzymes are considered a promising strategy for the treatment of several diseases. In this study, a quantitative structure-activity relationship (QSAR) modeling was e...

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Detalles Bibliográficos
Autores principales: Phanus-umporn, Chuleeporn, Prachayasittikul, Veda, Nantasenamat, Chanin, Prachayasittikul, Supaluk, Prachayasittikul, Virapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214779/
https://www.ncbi.nlm.nih.gov/pubmed/32398970
http://dx.doi.org/10.17179/excli2020-1096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214779/
https://www.ncbi.nlm.nih.gov/pubmed/32398970
http://dx.doi.org/10.17179/excli2020-1096

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