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Overexpression of Toll-Like Receptor 4 Affects Autophagy, Oxidative Stress, and Inflammatory Responses in Monocytes of Transgenic Sheep

Toll-like receptor 4 (TLR4) is a critical pattern recognition receptor that plays a critical role in the host innate immune system’s recognition of Gram-negative bacteria. Since it is the lipopolysaccharide (LPS) receptor, it links the activated inflammatory response with autophagy and oxidative str...

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Detalles Bibliográficos
Autores principales: Wang, Sutian, Song, Xuting, Zhang, Kunli, Deng, Shoulong, Jiao, Peixin, Qi, Meiyu, Lian, Zhengxing, Yao, Yuchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214805/
https://www.ncbi.nlm.nih.gov/pubmed/32432106
http://dx.doi.org/10.3389/fcell.2020.00248