A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients

Objectives: To assess whether the histopathological features of the synovium before starting treatment with the TNFi certolizumab-pegol could predict clinical outcome and examine the modulation of histopathology by treatment. Methods: Thirty-seven RA patients fulfilling UK NICE guidelines for biolog...

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Detalles Bibliográficos
Autores principales: Nerviani, Alessandra, Di Cicco, Maria, Mahto, Arti, Lliso-Ribera, Gloria, Rivellese, Felice, Thorborn, Georgina, Hands, Rebecca, Bellan, Mattia, Mauro, Daniele, Boutet, Marie-Astrid, Giorli, Giovanni, Lewis, Myles, Kelly, Stephen, Bombardieri, Michele, Humby, Frances, Pitzalis, Costantino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214807/
https://www.ncbi.nlm.nih.gov/pubmed/32431716
http://dx.doi.org/10.3389/fimmu.2020.00845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214807/
https://www.ncbi.nlm.nih.gov/pubmed/32431716
http://dx.doi.org/10.3389/fimmu.2020.00845

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