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Lidocaine mediates the progression of cerebral ischemia/reperfusion injury in rats via inhibiting the activation of NF-κB p65 and p38 MAPK

BACKGROUND: Lidocaine is a commonly used local anesthetic, and low-dose lidocaine has neuroprotective effects on cerebral ischemia/reperfusion (CI/R) injury; the mechanism for this, however, is still unclear. The aim of this study was to investigate the role and the possible mechanisms of lidocaine...

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Detalles Bibliográficos
Autores principales: Jiang, Rong, Liao, Juan, Yang, Meng-Chang, Deng, Jia, Hu, Yun-Xia, Li, Peng, Li, Mei-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214891/
https://www.ncbi.nlm.nih.gov/pubmed/32411771
http://dx.doi.org/10.21037/atm-20-3066