Cargando…
Lidocaine mediates the progression of cerebral ischemia/reperfusion injury in rats via inhibiting the activation of NF-κB p65 and p38 MAPK
BACKGROUND: Lidocaine is a commonly used local anesthetic, and low-dose lidocaine has neuroprotective effects on cerebral ischemia/reperfusion (CI/R) injury; the mechanism for this, however, is still unclear. The aim of this study was to investigate the role and the possible mechanisms of lidocaine...
Autores principales: | Jiang, Rong, Liao, Juan, Yang, Meng-Chang, Deng, Jia, Hu, Yun-Xia, Li, Peng, Li, Mei-Ting |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214891/ https://www.ncbi.nlm.nih.gov/pubmed/32411771 http://dx.doi.org/10.21037/atm-20-3066 |
Ejemplares similares
-
Lidocaine relieves murine allergic rhinitis by regulating the NF-κB and p38 MAPK pathways
por: Xiang, Jing, et al.
Publicado: (2022) -
Neuroprotective mechanism of salvianolic acid B against cerebral ischemia–reperfusion injury in mice through downregulation of TLR4, p‐p38MAPK, p‐JNK, NF‐κB, and IL‐1β
por: Zheng, Xiu‐fen, et al.
Publicado: (2023) -
Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury
por: Khan, Sana Irfan, et al.
Publicado: (2017) -
p38 MAPK Endogenous Inhibition Improves Neurological Deficits in Global Cerebral Ischemia/Reperfusion Mice
por: Hou, Kun, et al.
Publicado: (2022) -
Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways
por: Yue, Xin, et al.
Publicado: (2016)