Down-Regulated Exosomal MicroRNA-221 – 3p Derived From Senescent Mesenchymal Stem Cells Impairs Heart Repair

The composition and biological activity of donor cells is largely determined by the exosomes they secrete. In this study, we isolated exosomes from young (Young-Exo) and aged (Age-Exo) mesenchymal stem cells (MSCs) and compared their regeneration activity. Young Exo MSCs were more efficient than Age...

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Detalles Bibliográficos
Autores principales: Sun, Ling, Zhu, Wenwu, Zhao, Pengcheng, Zhang, Jian, Lu, Yao, Zhu, Yeqian, Zhao, Wei, Liu, Yaowu, Chen, Qiushi, Zhang, Fengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214920/
https://www.ncbi.nlm.nih.gov/pubmed/32432109
http://dx.doi.org/10.3389/fcell.2020.00263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214920/
https://www.ncbi.nlm.nih.gov/pubmed/32432109
http://dx.doi.org/10.3389/fcell.2020.00263

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