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Sirt6 in pro-opiomelanocortin neurons controls energy metabolism by modulating leptin signaling

OBJECTIVE: Sirt6 is an essential regulator of energy metabolism in multiple peripheral tissues. However, the direct role of Sirt6 in the hypothalamus, specifically pro-opiomelanocortin (POMC) neurons, controlling energy balance has not been established. Here, we aimed to determine the role of Sirt6...

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Detalles Bibliográficos
Autores principales: Tang, Qin, Gao, Yong, Liu, Qinhui, Yang, Xuping, Wu, Tong, Huang, Cuiyuan, Huang, Ya, Zhang, Jinhang, Zhang, Zijing, Li, Rui, Pu, Shiyun, Zhang, Guorong, Zhao, Yingnan, Zhou, Jian, Huang, Hui, Li, Yanping, Jiang, Wei, Chang, Yongsheng, He, Jinhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215198/
https://www.ncbi.nlm.nih.gov/pubmed/32278654
http://dx.doi.org/10.1016/j.molmet.2020.100994