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Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand Activation

Receptor tyrosine kinases (RTKs) orchestrate cell motility and differentiation. Deregulated RTKs may promote cancer and are prime targets for specific inhibitors. Increasing evidence indicates that resistance to inhibitor treatment involves receptor cross-interactions circumventing inhibition of one...

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Detalles Bibliográficos
Autores principales: Harwardt, Marie-Lena I.E., Schröder, Mark S., Li, Yunqing, Malkusch, Sebastian, Freund, Petra, Gupta, Shashi, Janjic, Nebojsa, Strauss, Sebastian, Jungmann, Ralf, Dietz, Marina S., Heilemann, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215329/
https://www.ncbi.nlm.nih.gov/pubmed/32316583
http://dx.doi.org/10.3390/ijms21082803